publication . Article . 2014

Effects of neonatal surgical castration and immunocastration in male pigs on blood T lymphocytes and health markers.

C. Leclercq; A. Prunier; E. Merlot;
Open Access English
  • Published: 17 Apr 2014
  • Country: Algeria
<jats:p>Surgical castration in pig husbandry is criticized for welfare reasons. Thus, it is necessary to evaluate alternative ways of rearing male pigs, such as entire or immunocastrated animals. Immunocastration is a vaccination directed against gonadotropin-releasing hormone (GnRH) to suppress the production of sexual hormones. This study aimed at investigating the effects of these two methods of castration in comparison with intact male pigs on blood T-lymphocyte subsets and function, the immunoglobulin (Ig) response to an influenza vaccine and health markers during sexual development. A total of 70 animals were allocated to three experimental groups: entire ...
free text keywords: Immunologie, Immunology, Biologie animale, Animal biology, porc, castration chirurgicale, cellule t, lymphocyte t, immunocastration, testosterone, [SDV.IMM]Life Sciences [q-bio]/Immunology, [SDV.BA]Life Sciences [q-bio]/Animal biology, Animal Science and Zoology, Endocrinology, medicine.medical_specialty, medicine, Biology, Surgical castration, Internal medicine
30 references, page 1 of 2

Allrich RD, Christenson RK, Ford JJ and Zimmerman DR 1982. Pubertal development of the boar -testosterone, estradiol-17-beta, cortisol and LH 842 Bouman A, Heineman MJ and Faas MM 2005. Sex hormones and the immune response in humans. Human Reproduction Update 11, 411-423.

Brunius C, Zamaratskaia G, Andersson K, Chen G, Norrby M, Madej A and Lundstrom K 2011. Early immunocastration of male pigs with Improvac (R) - effect on boar taint, hormones and reproductive organs. Vaccine 29, 9514-9520. [OpenAIRE]

Caccamo N, Dieli F, Wesch D, Jomaa H and Eberl M 2006. Sex-specific phenotypical and functional differences in peripheral human V gamma 9/V delta 2 T cells. Journal of Leukocyte Biology 79, 663-666.

Chen A, Ganor Y, Rahimipour S, Ben-Aroya N, Koch Y and Levite M 2002.

The neuropeptides GnRH-II and GnRH-I are produced by human T cells and trigger laminin receptor gene expression, adhesion, chemotaxis and homing to specific organs. Nature Medicine 8, 1421-1426.

Claus R, Lacorn M, Danowski K, Pearce MC and Bauer A 2007. Short-term endocrine and metabolic reactions before and after second immunization against GnRH in boars. Vaccine 25, 4689-4696. [OpenAIRE]

Colenbrander B, Dejong FH and Wensing CJG 1978. Changes in serum testosterone concentrations in male pig during development. Journal of Reproduction and Fertility 53, 377-380. [OpenAIRE]

Colenbrander B, Meijer JC, Macdonald AA, Vandewiel DFM, Engel B and de Jong FH 1987. Feedback-regulation of gonadotropic hormone secretion in neonatal pigs. Biology of Reproduction 36, 871-877. [OpenAIRE]

Couret D, Jamin A, Kuntz-Simon G, Prunier A and Merlot E 2009. Maternal stress during late gestation has moderate but long-lasting effects on the immune system of the piglets. Veterinary Immunology Immunopathology 131, 17-24.

Ellis TM, Moser MT, Le PT, Flanigan RC and Kwon ED 2001. Alterations in peripheral B cells and B cell progenitors following androgen ablation in mice.

Internal Immunology 13, 553-558.

Gould KG, Akinbami MA and Mann DR 1998. Effect of neonatal treatment with a gonadotropin releasing hormone antagonist on developmental changes in circulating lymphocyte subsets: a longitudinal study in male rhesus monkeys. Developmental and Comparative Immunology 22, 457-467.

Henry Y, Dauloudet C, Kerisit R, Lefeuve P, Gaye A, Denechaud MF and Bourdon D 1970. Effets nutritionnels de l'incorporation de cellulose purifiée dans le régime du porc en croissance-finition. III-Incidence sur le développement des ulcères gastro-oesophagiens. Annales de Zootechnie 19, 117-141. [OpenAIRE]

Hirakata A, Okumi M, Griesemer AD, Shimizu A, Nobori S, Tena A, Moran S, Arn S, Boyd RL, Sachs DH and Yamada K 2010. Reversal of age-related thymic involution by an LHRH agonist in miniature swine. Transplant Immunology 24, 76-81.

Jacobson JD and Ansari MA 2004. Immunomodulatory actions of gonadal steroids may be mediated by gonadotropin-releasing hormone. Endocrinology 145, 330-336.

30 references, page 1 of 2
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publication . Article . 2014

Effects of neonatal surgical castration and immunocastration in male pigs on blood T lymphocytes and health markers.

C. Leclercq; A. Prunier; E. Merlot;