publication . Conference object . Part of book or chapter of book . 2013

Prediction of net hepatic release of glucose using a ‘hybrid’ mechanistic model in ruminants applied to positive energy balance

Hélène Lapierre; Lahlou Bahloul; Pierre Noziere; Isabelle Ortigues-Marty; Daniel Sauvant; Jean Vernet;
Open Access English
  • Published: 09 Sep 2013
  • Publisher: HAL CCSD
  • Country: France
Abstract
Ruminants depend on hepatic gluconeogenesis to meet most of their metabolic demand for glucose which relies on availability of precursors from diet supply and animal requirements (Loncke et al., 2010). Several mechanistic models of the metabolic fate of nutrients across the liver exist that have been parameterized for dairy cows. They cannot be directly used to predict hepatic gluconeogenesis in all types of ruminants in different physiological status. A hybrid mechanistic model of nutrient fluxes across the liver is presently being developed (Bahloul et al., 2012), that is calibrated empirically based on meta-analysis (Sauvant and Mertens, 2008) to be applicabl...
Subjects
free text keywords: [SDV]Life Sciences [q-bio], [ SDV ] Life Sciences [q-bio], glucose, nutriment, néoglucogenèse, ruminant, foie, Hepatic gluconeogenesis, Energy balance, Positive energy, Animal science, Nutrient flux, Metabolic demand, Biology, Nutrient, Biochemistry
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