Identifying antigenicity associated sites in highly pathogenic H5N1 influenza virus hemagglutinin by using sparse learning

Article, Other literature type English OPEN
Cai, Zhipeng ; Ducatez, Mariette F. ; Yang, Jialiang ; Zhang, Tong ; Long, Li-Ping ; Boon, Adrianus C. ; Webby, Richard J. ; Wan, Xiu-Feng (2012)
  • Related identifiers: doi: 10.1016/j.jmb.2012.05.011, pmc: PMC3412944
  • Subject: Emerging diseases | Maladies émergentes | Infectious diseases | Virologie | Article | Immunologie | Médecine humaine et pathologie | Virology | antibody binding site;antigenicity;sparse learning;antigenic drift;H5N1 | Maladies infectieuses | Human health and pathology | Immunology
    mesheuropmc: virus diseases

Since the isolation of A/goose/Guangdong/1/1996 (H5N1) in farmed geese in southern China, highly pathogenic H5N1 avian influenza viruses have posed a continuous threat to both public and animal health. The non-synonymous mutation of the H5 hemagglutinin gene has resulte... View more
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