Selective bromination of 4-chloro-1-indanone and synthesis of (4-chloro-2, 3-dihydro-1H-indene-2-yl)methanamine

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Jasouri, S.; Khalafy, J.; Badali, M.; Piltan, M.;
(2010)
  • Publisher: The South African Chemical Institute
  • Subject: GABA B receptors | cyanation | Indanone | reduction | bromination

The synthesis of 4-chloro-1-indanone in four steps from 2-chlorobenzaldehyde was investigated. Bromination of this compound under various conditions occurred in the cyclopentanone ring, producing mono- and dibromo derivatives. Cyanation of 2-bromo-4-chloro-1-indanone fo... View more
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