Synthesis of 9H-indeno [1, 2-b] pyrazine and 11H-indeno [1, 2-b] quinoxaline derivatives in one-step reaction from 2-bromo-4-chloro-1-indanone

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Jasouri, S.; Khalafy, J.; Badali, M.; Prager, R.H.;
(2011)
  • Publisher: The South African Chemical Institute
  • Subject: pyrazine | 2-bromo-4-chloro-1-indanone | debromination | diaminopyridine | quinoxaline | indeno

The reaction of 2-bromo-4-chloro-1-indanone with 2,3-diaminomaleonitrile, benzene-1,2-diamine and 4-methylbenzene-1,2-diamine in glacial acetic acid gave 8-chloro-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile, 1-chloro-11H-indeno[1,2-b]quinoxa-line and 1-chloro-7-methyl-1... View more
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