BRAFV600E mutation as a predictor of thyroid malignancy in indeterminate nodules: a systematic review and meta-analysis

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Jinih, Marcel; Foley, Niamh M.; Osho, Olakunle; Houlihan, Lena; Toor, Asad Ali; Khan, Jehan Z.; Achackzai, Akbar A.; Redmond, H. Paul;
  • Publisher: Elsevier Ltd
  • Related identifiers: doi: 10.1016/j.ejso.2016.11.003
  • Subject: Indeterminate thyroid nodule | BRAF V600E mutation | Thy3a | Thy3f | Thy4

Background: Thyroid nodules are usually diagnosed using fine-needle aspiration (FNA). The sensitivity limitations of FNA result in 10–30% of nodules being classified as “indeterminate”. The BRAFV600E mutation is associated with papillary thyroid carcinoma (PTC). We cond... View more
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