publication . Other literature type . 2016

The Role of GPR84 in Medium-chain Saturated Fatty Acid Taste Transduction

Liu, Yan;
Open Access
  • Published: 01 May 2016
  • Publisher: DigitalCommons@USU
  • Country: United States
Abstract
Previous research has shown the gustatory recognition of the long-chain unsaturated fatty acids. In this study, I showed for the first time that medium-chain saturated fatty acids (MCFAs) are effective taste stimuli at both the cellular and behavioral levels. The mechanisms of gustatory recognition of MCFAs in mice were also partially elucidated using pharmaceutical approaches. The inward currents induced by capric acid in mouse taste cells were significantly inhibited by the antagonists of G-protein signaling, protein kinase A (PKA), and protein kinase C (PKC), but they were not affected by the phospholipase C (PLC) and phosphodiesterase (PDE) inhibitors, which...
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free text keywords: Biology
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DigitalCommons@USU
Other literature type . 2016
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