publication . Other literature type . 2010

Select tissue mineralconcentrations and chronic wasting disease status in mule deer from north-central Colorado

Wolfe, Lisa L.; Conner, Mary M.; Bedwell, Cathy L.; Lukacs, Paul M.; Miller, Michael W.;
Open Access
  • Published: 25 Feb 2010
  • Publisher: Hosted by Utah State University Libraries
  • Country: United States
Abstract
Trace mineral imbalances have been suggested as having a causative or contributory role in chronic wasting disease (CWD), a prion disease of several North American cervid species. To begin exploring relationships between tissue mineral concentrations and CWD in natural systems, we measured liver tissue concentrations of copper, manganese, and molybdenum in samples from 447 apparently healthy, adult (≥2 yr old) mule deer (Odocoileus hemionus) culled or vehicle killed from free-ranging populations in north-central Colorado, United States, where CWD occurs naturally; we also measured copper concentrations in brain-stem (medulla oblongata at the obex) tissue from 18...
Subjects
Medical Subject Headings: animal diseases
free text keywords: Chronic wasting disease (CWD), copper (Cu), manganese (Mn), molybdenum (Mo), mule deer, Odocoileus hemionus, prion, trace mineral, Environmental Sciences
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Other literature type . 2010
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