Robust gap repair in the contractile ring ensures timely completion of cytokinesis

Article English OPEN
Silva, Ana M.; Osório, Daniel S.; Pereira, Antonio J.; Maiato, Helder; Pinto, Inês Mendes; Rubinstein, Boris; Gassmann, Reto; Telley, Ivo Andreas; Carvalho, Ana Xavier;
  • Publisher: Rockefeller University Press
  • Journal: The Journal of Cell Biology,volume 215,issue 6,pages789-799 (issn: 0021-9525, eissn: 1540-8140)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1083/jcb.201605080, pmc: PMC5166501
  • Subject: Bridged Bicyclo Compounds, Heterocyclic/pharmacology | Caenorhabditis elegans/cytology | Embryo, Nonmammalian/cytology | 38 | cytokinesis | ring constriction | Thiazolidines/pharmacology | Caenorhabditis elegans/embryology | Actomyosin/metabolism | Microsurgery | Caenorhabditis elegans/drug effects | Lasers | Report | Animals | Research Articles | Caenorhabditis elegans embryos | 21 | 10

Cytokinesis in animal cells requires the constriction of an actomyosin contractile ring, whose architecture and mechanism remain poorly understood. We use laser microsurgery to explore the biophysical properties of constricting rings in Caenorhabditis elegans embryos. L... View more