Robust gap repair in the contractile ring ensures timely completion of cytokinesis.

Article English OPEN
Silva, AM ; Osório, DS ; Pereira, AJ ; Maiato, H ; Pinto, IM ; Rubinstein, B ; Gassmann, R ; Telley, IA ; Carvalho, AX (2016)
  • Publisher: Rockefeller University Press
  • Journal: volume 215, issue 6, pages 789-799 (issn: 0021-9525, eissn: 1540-8140)
  • Related identifiers: doi: 10.1083/jcb.201605080, pmc: PMC5166501
  • Subject: Bridged Bicyclo Compounds, Heterocyclic/pharmacology | Caenorhabditis elegans/cytology | 38 | Embryo, Nonmammalian/cytology | Cytokinesis | ring constriction | Thiazolidines/pharmacology | Caenorhabditis elegans/embryology | Actomyosin/metabolism | Microsurgery | Caenorhabditis elegans/drug effects | Lasers | Report | Research Articles | Animals | Caenorhabditis elegans embryos | 21 | 10

Cytokinesis in animal cells requires the constriction of an actomyosin contractile ring, whose architecture and mechanism remain poorly understood. We use laser microsurgery to explore the biophysical properties of constricting rings in Caenorhabditis elegans embryos. L... View more