Novel micellar systems for the formulation of poorly water soluble drugs : biocompatibility aspects and pharmaceutical applications

Doctoral thesis, Other literature type English OPEN
Dumontet Mondon, Karine;
(2010)
  • Publisher: Université de Genève
  • Identifiers: doi: 10.13097/archive-ouverte/unige:17166
  • Subject: Toxicity | Skin deposition | Econazole nitrate | Photodiagnosis | Biocompatibility | Ovarian cancer | Cyclosporin A | Drug delivery | Micelles | Hypericin | CAM | Hexyl substituted polylactides | Antifungal | Polymeric micelles | info:eu-repo/classification/ddc/615 | HexPLA | Topical application | TEM
    • ddc: ddc:615

Amongst the large number of novel drugs, 95% are lipophilic and poorly water soluble. Particularly, this renders their aqueous formulation very difficult. In this regard this thesis focused on polymeric micelles based on novel MPEG-hexPLA copolymers forming a hydrophili... View more
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