Novel micellar systems for the formulation of poorly water soluble drugs : biocompatibility aspects and pharmaceutical applications

Doctoral thesis English OPEN
Dumontet Mondon, Karine;
(2010)
  • Publisher: Université de Genève
  • Related identifiers: doi: 10.13097/archive-ouverte/unige:17166
  • Subject: Antifungal | Biocompatibility | CAM | Cyclosporin A | Drug delivery | Econazole nitrate | Hexyl substituted polylactides | Hypericin | Micelles | Toxicity | Ovarian cancer | HexPLA | Photodiagnosis | Polymeric micelles | Skin deposition | TEM | Topical application
    • ddc: ddc:615

Amongst the large number of novel drugs, 95% are lipophilic and poorly water soluble. Particularly, this renders their aqueous formulation very difficult. In this regard this thesis focused on polymeric micelles based on novel MPEG-hexPLA copolymers forming a hydrophili... View more
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