publication . Article . 2011

Survival predictors for second-line chemotherapy in Caucasian patients with metastatic gastric cancer

P Bohanes; DS Courvoisier; TV Perneger; P Morel; O Huber; AD Roth;
Open Access English
  • Published: 26 Aug 2011
  • Country: Switzerland
Abstract
Summary PRINCIPLES: There are very limited data suggesting a benefit for second-line chemotherapy in advanced gastric cancer. Therefore, the number of patients who receive further treatment after failure of first-line chemotherapy varies considerably, ranging from 14% to 75%. In the absence of a demonstrated survival benefit of second-line chemotherapy, appropriate selection of patients based on survival predictors is essential. However, no clinico-pathologic parameters are currently widely adopted in clinical practice. We looked exclusively at Caucasian patients with metastatic gastric cancer treated with second-line chemotherapy to see if we could establish pr...
Subjects
free text keywords: Adult, Aged, Antineoplastic Combined Chemotherapy Protocols/therapeutic use, Carcinoembryonic Antigen/blood, Disease-Free Survival, European Continental Ancestry Group, Female, Humans, Male, Middle Aged, Neoplasm Metastasis, Prognosis, Proportional Hazards Models, Retrospective Studies, Stomach Neoplasms/drug therapy/pathology/surgery, ddc:616, ddc:617, General Medicine, Confidence interval, Gastrectomy, medicine.medical_treatment, medicine, Oncology, medicine.medical_specialty, Cancer, medicine.disease, Internal medicine, Surgery, Intensive care medicine, Hazard ratio, business.industry, business, Carcinoma, Proportional hazards model, Univariate analysis, Chemotherapy
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publication . Article . 2011

Survival predictors for second-line chemotherapy in Caucasian patients with metastatic gastric cancer

P Bohanes; DS Courvoisier; TV Perneger; P Morel; O Huber; AD Roth;