publication . Article . 2016

Reduced need for grafting and low incidence of hypertrophic scarring in burns after enzymatic debridement

Corrales-Benítez, Carlos; Martínez-Méndez, José Ramón; González-Miranda, Álvaro; Serrano-Alonso, Maite; Casado-Pérez, César;
Open Access Spanish; Castilian
  • Published: 01 Oct 2016
  • Publisher: Sociedad Española de Cirugía Plástica, Reparadora y Estética (SECPRE)
  • Country: Spain
Abstract
Background and Objective. Early burn scar removal is the standard of care for burn patients; excisional debridement, however, often leads to excision of dermal remnants, making autografting unavoidable. Enzymatic debridement with proteolytic enzymes enriched in Bromelain (Nexobrid®) leaves these dermal remnants to allow spontaneous healing of partial thickness burns. This study evaluates if Nexobrid® (MediWound Ltd., Israel) reduces the need for surgery and autografting in intermediate and deepdermal burns, the reduction in the excised and grafted area, and the development of hypertrophic scarring. Patients and Methods.We conduct a prospective study between Janu...
Subjects
free text keywords: Autografting, Bromelain, Burns, Enzymatic debridement, Hypertrophic scar, Medicina
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