publication . Thesis . 2017

Studies towards a total synthesis of tagetitoxin

Mahoney, Brian;
Open Access
  • Published: 01 Mar 2017
  • Country: United Kingdom
Abstract
Tagetitoxin was first isolated over thirty five years ago and a total synthesis has not been achieved to date. A vast amount of research has been carried out on the biological activity of tagetitoxin with hundreds of literature reports. However, very few papers have been published regarding the synthesis and within this thesis we will explore a number of synthetic pathways some towards tagetitoxin. The first chapter reviews previous developments regarding the total synthesis of tagetitoxin. It also covers the discovery and biological work that has being carried out in identifying the structure and the biological activity of tagetitoxin. The second part reports m...
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