publication . Article . 2015

Does dysfunction of the mirror neuron system contribute to symptoms in amyotrophic lateral sclerosis

Roger N. Lemon; Martin R. Turner; Matthew C. Kiernan; Andrew Eisen; Michael Hornberger;
Open Access English
  • Published: 01 Jul 2015
  • Country: United Kingdom
There is growing evidence that mirror neurons, initially discovered over two decades ago in the monkey, are present in the human brain. In the monkey, mirror neurons characteristically fire not only when it is performing an action, such as grasping an object, but also when observing a similar action performed by another agent (human or monkey). In this review we discuss the origin, cortical distribution and possible functions of mirror neurons as a background to exploring their potential relevance in amyotrophic lateral sclerosis (ALS). We have recently proposed that ALS (and the related condition of frontotemporal dementia) may be viewed as a failure of interli...
free text keywords: Physiology (medical), Sensory Systems, Neurology, Clinical Neurology, Mirror neuron, Human brain, medicine.anatomical_structure, medicine, Frontotemporal dementia, medicine.disease, Motor cortex, Pyramidal tracts, Primary motor cortex, Amyotrophic lateral sclerosis, Psychology, Corticospinal tract, Neuroscience
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