Screening for GPR101 defects in pediatric pituitary corticotropinomas.

Article, Other literature type English OPEN
Trivellin, Giampaolo; Correa, Ricardo R.; Batsis, Maria; Faucz, Fabio R.; Chittiboina, Prashant; Bjelobaba, Ivana; Larco, Darwin O.; Quezado, Martha; Daly, Adrian F.; Stojilkovic, Stanko S.; Wu, T. John; Beckers, Albert; Lodish, Maya; Stratakis, Constantine A.;
(2016)
  • Related identifiers: pmc: PMC5017905, doi: 10.1530/ERC-16-0091
  • Subject: : Endocrinology, metabolism & nutrition [Human health sciences] | : Endocrinologie, métabolisme & nutrition [Sciences de la santé humaine] | Article

Cushing disease (CD) in children is caused by adrenocorticotropic hormone (ACTH)-secreting pituitary adenomas. Germline or somatic mutations in genes such as MEN1, CDKIs, AIP, and USP8 have been identified in pediatric CD, but the genetic defects in a significant percen... View more
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