Study of carvedilol by combined Raman spectroscopy and ab initio MO calculations

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Marques, M. P. M.; Oliveira, P. J.; Moreno, A. J. M.; Carvalho, L. A. E. Batista de;
(2002)

The novel cardioprotective drug carvedilol was studied by both Raman spectroscopy and ab initio molecular orbital methods (using the density functional theory approach). The spectra, acquired both for the solid samples and DMSO solutions as a function of pH, were assign... View more
  • References (15)
    15 references, page 1 of 2

    1. Ruffolo RR Jr, Boyle DA, Brooks DP, Feuerstein GZ, Venuti RP, Lukas MA, Poste G. Cardiovasc. Drug Rev. 1992; 10: 127.

    2. Dunn CJ, Lea AP, Wagstaff AJ. Drugs 1997; 54: 161.

    3. Oliveira PJ, Santos DJ, Moreno AJM. Arch. Biochem. Biophys. 2000; 374: 279.

    4. Abreu RMV, Santos DJ, Moreno AJM. J. Pharmacol. Exp. Ther. 2000; 295: 1022.

    5. Oliveira PJ, Coxito PM, Rolo AP, Santos DJ, Palmeira CM, Moreno AJM. Eur. J. Pharmacol. 2001; 412: 231.

    6. Santos DJ, Moreno AJM. Biochem. Pharmacol. 2001; 61: 155.

    7. Oliveira PJ, Marques MPM, Batista de Carvalho LAE, Moreno AJM. Biochem. Biophys. Res. Commun. 2000; 276: 82.

    8. Frisch MJ et al. Gaussian 98, Revision A.3. Gaussian: Pittsburgh, PA, 1998.

    9. Binkley JS, Pople JA, Hehre WJ. J. Am. Chem. Soc. 1980; 102: 939.

    10. Peng C, Ayala PY, Schlegel HB, Frisch MJ. J. Comput. Chem. 1996; 17: 49.

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