Add-on treatment with N-acetylcysteine for bipolar depression:a 24-week randomized double-blind parallel group placebo-controlled multicentre trial (NACOS-study protocol)

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Ellegaard, Pernille Kempel; Licht, Rasmus Wentzer; Poulsen, Henrik Enghusen; Nielsen, René Ernst; Berk, Michael; Dean, Olivia May; Mohebbi, Mohammadreza; Nielsen, Connie Thuroee;
  • Publisher: Springer Berlin Heidelberg
  • Journal: volume 6issn: 2194-7511, eissn: 2194-7511
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC6162004, doi: 10.1186/s40345-018-0117-9
  • Subject: Acetylcysteine | Treatment | /dk/atira/pure/researchoutput/pubmedpublicationtype/D016428 | Neurosciences. Biological psychiatry. Neuropsychiatry | Urine | RC321-571 | Psychiatry | Blood | Research | Bipolar disorder | Genetics | Inflammation | Neurophysiology and neuropsychology | Journal Article | Depression | QP351-495 | Oxidative stress

<p>BACKGROUND: Oxidative stress and inflammation may be involved in the development and progression of mood disorders, including bipolar disorder. Currently, there is a scarcity of useful treatment options for bipolar depressive episodes, especially compared with the ef... View more
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