publication . Conference object . 2012

Phenolic compounds and bioactive properties of wild German and Roman chamomiles

Guimarães, Rafaela; Barros, Lillian; Dueñas, Montserrat; Calhelha, Ricardo C.; Carvalho, Ana Maria; Santos-Buelga, Celestino; Queiroz, Maria João R.P.; Ferreira, Isabel C.F.R.;
Open Access English
  • Published: 01 Jan 2012
  • Country: Portugal
Abstract
Natural products represent a rich source of biologically active compounds and are an example of molecular diversity, with recognized potential in drug discovery. In the present work, methanolic extracts of Matricaria recutita L. (German chamomile) and Chamaemelum nobile L. (Roman chamomile) and their decoction and infusion (the most consumed preparations of these herbs) were submitted to an analysis of phenolic compounds and bioactivity evaluation. Phenolic compounds were characterized by HPLC-DAD/ESI-MS. The bioactivity of the samples was tested in human tumour cell lines (breast- MCF-7, non-small cell lung- NCI-H460, colon- HCT-15, cervical- HeLa and hepatocel...
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