publication . Other literature type . Article . 2009

Surface Characteristics, Copper Release, and Toxicity of Nano- and Micrometer-Sized Copper and Copper(II) Oxide Particles: A Cross-Disciplinary Study

Klara Midander; Pontus Cronholm; Hanna L. Karlsson; Karine Elihn; Lennart Möller; Christofer Leygraf; Inger Odnevall Wallinder;
Open Access
  • Published: 06 Feb 2009
  • Publisher: Wiley
  • Country: Poland
Abstract
An interdisciplinary and multianalytical research effort is undertaken to assess the toxic aspects of thoroughly characterized nano- and micrometer-sized particles of oxidized metallic copper and copper(II) oxide in contact with cultivated lung cells, as well as copper release in relevant media. All particles, except micrometer-sized Cu, release more copper in serum-containing cell medium (supplemented Dulbecco's minimal essential medium) compared to identical exposures in phosphate-buffered saline. Sonication of particles for dispersion prior to exposure has a large effect on the initial copper release from Cu nanoparticles. A clear size-dependent effect is obs...
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free text keywords: Biotechnology, Engineering (miscellaneous), Biomaterials, cytotoxicity, DNA damage, nanoparticles, particle characterization, Cell Line, Metal Nanoparticles, Microscopy, Electron, Scanning, Spectrophotometry, Atomic, Surface Properties, Metal, visual_art.visual_art_medium, visual_art, Copper toxicity, medicine.disease, medicine, Nanoparticle, Sonication, Copper, chemistry.chemical_element, chemistry, Metallurgy, Nanometre, Oxide, chemistry.chemical_compound, Materials science, Copper(II) oxide, Nuclear chemistry
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Article . 2009
Provider: Crossref
http://dx.doi.org/10.1002/smll...
Other literature type . 2009
Provider: Datacite
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