publication . Article . 1994

Glycosaminoglycan-sac formation in vitro. Interactions between normal and malignant cells

Logothetou-Rella, H.;
Open Access English
  • Published: 01 Jan 1994
  • Publisher: Murcia : F. Hernández
The interaction of monolayer normal human or normal rat cells with suspension Walker rat tumor cells was demonstrated cytologically, during a cocultivation period of thirty days. At ten days, Walker rat tumor cells were interiorized in the cytoplasm of the normal monolayer host cells. At twenty days, degeneration of the interiorized tumor cells followed by mucification led to glycosaminoglycan-sac formation. At thirty days, tumor nodules and protease (a,- chymotrypsin)- bound glycosaminoglycan(s) extracellular matrix, transversing the culture in membranous rivulets, were formed. The overall interaction resulted in ...
free text keywords: Emperipolesis, Cannibalism, :6 - Ciencias aplicadas::61 - Medicina [CDU]
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