publication . Article . 2007

Short-term exposure of mice to gasoline vapor increases the metallothionein expression in the brain, lungs and kidney

Grebić, D.; Hrvoje Jakovac; Mrakovčić-Šutić, I.; Tomac, J.; Bulog, A.; Mićović, V.; Radošević-Stašić, B.;
Open Access
  • Published: 01 Jan 2007
  • Country: Spain
Abstract
Environmental airborne pollution has been repeatedly shown to affect multiple aspects of brain and cardiopulmonary function, leading to cognitive and behavioral changes and to the pronounced inflammatory response in the respiratory airways. Since in the cellular defense system the important role might have stress proteins-metallothionein (MT)-I and MT-II, which are involved in sequestration and dispersal of metal ions, regulation of the biosynthesis and activities of zincdependent transcription factors, as well as in cellular protection from reactive oxygen species, genotoxicity and apoptosis, in this study we investigated their expression in the brain, lungs an...
Subjects
free text keywords: Gasoline inhalation, Kidney, 615 - Farmacología. Terapéutica. Toxicología. Radiología
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