Lead-induced DNA damage in Vicia faba root cells: Potential involvement of oxidative stress

Article English OPEN
Pourrut, Bertrand ; Jean, Séverine ; Silvestre, Jérôme ; Pinelli, Eric (2011)
  • Publisher: Elsevier
  • Journal: Mutation Research - Genetic Toxicology and Environmental Mutagenesis (issn: 1383-5718)
  • Related identifiers: doi: 10.1016/j.mrgentox.2011.09.001
  • Subject: Genotoxicity | Biodiversité et Ecologie | Comet assay | DNA breakages | Reactive oxygen species | Génie chimique | Micronucleus test | Heavy metal
    mesheuropmc: food and beverages

Genotoxic effects of lead (0–20 µM) were investigated in whole-plant roots of Vicia faba L., grown hydroponically under controlled conditions. Lead-induced DNA damage in V. faba roots was evaluated by use of the comet assay, which allowed the detection of DNA strand-bre... View more
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