publication . Book . 2015

EFSA CONTAM Panel (EFSA Panel on Contaminants in the Food Chain), 2015. Scientific Opinion on the risks to public health related to the presence of nickel in food and drinking water

Open Access English
  • Published: 01 Jan 2015
  • Publisher: Europen Food Safety Authority
  • Country: Denmark
EFSA received a request from the Hellenic Food Authority (EFET) for a scientific opinion on the risk to human health from the presence of nickel (Ni) in food, particularly in vegetables. The EFSA Panel on Contaminants in the Food Chain (CONTAM Panel) decided to extend the risk assessment also to drinking water. The reproductive and developmental toxicity in experimental animals was selected as the critical effect for the assessment of chronic effects of Ni. A tolerable daily intake of 2.8 µg Ni/kg body weight (b.w.) per day was derived from a lower 95 % confidence limit for a benchmark dose at 10 % extra risk (BMDL10) of 0.28 mg/kg b.w. for post-implantation fet...
free text keywords: Nickel, Chemistry, Human dietary exposure, Toxicity, Risk assessment, Benchmark dose, Margin of exposure (MOE), Tolerable daily intake (TDI)
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