publication . Conference object . 2011

The chemical heritage of Aspergillus flavus in A. oryzae RIB 40

Christian Rank; Marie Louise Klejnstrup; Lene Maj Petersen; Jens Frisvad; Thomas Ostenfeld Larsen;
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  • Published: 01 Jan 2011
  • Country: Denmark
Abstract
Aspergillus oryzae is a very important species in biotechnology and has been used for centuries in traditional Asian fermentation. The RIB40 strain is particularly interesting as it was one of the first genome sequenced Aspergilli together with A. flavus, a prominent food and feed contaminant capable of producing aflatoxin. These species can be perceived as ecotypes. We have analyzed A. oryzae RIB40 and found that the chemical potential could be enhanced significantly under certain conditions. Delicate analysis of their metabolic profiles allow for chemical insight on the transcription level with indications to specific genetic changes. Several new metabolites a...
Subjects
Medical Subject Headings: food and beveragesskin and connective tissue diseases
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