publication . Doctoral thesis . 2015

Morphological and Biochemical Characterization of Bovine Congenital Psudomyotonia

Dorotea, Tiziano;
Open Access
  • Published: 20 Mar 2015
  • Country: Italy
Abstract
The Ca2+-ATPase of sarco(endo)plasmic reticulum (SERCA) is a protein of about 110 kDa member of the P-type ATPases family. SERCA pumps utilize the energy derived from the hydrolysis of a molecule of ATP to transport two Ca2+ ions across the Sarcoplasmic Reticulum (SR) membrane to decrease the Ca2+ concentration in the cytosol. SERCA isoform 1a (SERCA1a) is the mainly expressed isoform in adult fast-twitch muscle fibre and it is both structurally and functionally the best characterized member of the P-type ion translocating ATPases. An inherited muscle disorder defined as Bovine Congenital Pseudomyotonia (PMT) has been recently described in two important Italian ...
Subjects
free text keywords: VET/01 Anatomia degli animali domestici
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Doctoral thesis . 2015
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