publication . Doctoral thesis . 2016

BDNF, impulsiveness and avoidant focused coping in suicide attempters

AMBRUS, LIVIA;
Open Access English
  • Published: 01 Jan 2016
  • Publisher: Lund University: Faculty of Medicine
  • Country: Sweden
Abstract
Brain-derived neurotrophic factor (BDNF) is an important protein for neuroplasticity and neurogenesis. In this thesis the role of BDNF, in suicidal behaviour was investigated with focus on possible risk factors for suicidal behaviour such as avoidant focused coping, dysfuntional personality traits like impulsiveness and hyperactivity of the Hypothalamic-Pituitary-Adrenal (HPA) axis.Paper I: The association between avoidant focused coping and the BDNF Val66Met gene polymorphism in two different cohorts of suicide attempters was investigated. The Met allele of this gene polymorphism was associated with increased use of avoidant focused coping, irrespectively of ag...
Subjects
free text keywords: Medical and Health Sciences, BDNF, Aviodant coping, Suicide Attempters, HPA axis, Impulsvieness, Avoidant focused coping, attempted suicide, impulsiveness
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