Structure-function studies of the staphylococcal methicillin resistance antirepressor MecR2

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Arede, Pedro; Botelho, Tiago O.; Guevara, Tibisay; Usón, Isabel; Oliveira, Duarte C.; Gomis-Rüth, F. Xavier; Gomis-Rüth, F. Xavier;

Methicillin resistance in Staphylococcus aureus is elicited by the MecI-MecR1-MecA axis encoded by the mec locus. Recently, MecR2 was also identified as the third regulator of mec through binding of the methicillin repressor, MecI. Here we show that plasmid-encoded full... View more
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