Increased T cell trafficking as adjunct therapy for HIV-1

Article OPEN
Fryer, HR; Wolinsky, SM; McLean, AR;
(2018)
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS Computational Biology,volume 14,issue 3 (issn: 1553-734X, eissn: 1553-7358)
  • Related identifiers: pmc: PMC5864072, doi: 10.1371/journal.pcbi.1006028
  • Subject: Microbial Control | Microbial Pathogens | Antivirals | Research Article | Anatomy | Antiretroviral Therapy | Preventive Medicine | T Helper Cells | Pathology and Laboratory Medicine | Antimicrobials | Lymphatic System | Vaccination and Immunization | Immunodeficiency Viruses | Retroviruses | HIV-1 | Viral Persistence and Latency | White Blood Cells | HIV | Pathogens | Antiretrovirals | Lymphoid Tissue | Public and Occupational Health | Pharmacology | Immunology | Antiviral Therapy | Lentivirus | Cellular Types | Viruses | Biology and Life Sciences | Drugs | Blood Cells | Microbiology | Immune Cells | Animal Cells | QH301-705.5 | Viral Replication | Medical Microbiology | Viral Pathogens | Cell Biology | RNA viruses | Virology | T Cells | Organisms | Medicine and Health Sciences | Biology (General)

Author summary Despite the success of potent antiretroviral therapy in suppressing the amount of virus in peripheral blood for long periods of time, a reservoir of infectious virus persists in CD4 T cells, implying the need for long-term treatment. Strategies to control... View more