Sasquatch: predicting the impact of regulatory SNPs on transcription factor binding from cell- and tissue-specific DNase footprints

Other literature type, Article English OPEN
Schwessinger, Ron; Suciu, Maria C.; McGowan, Simon J.; Telenius, Jelena; Taylor, Stephen; Higgs, Doug R.; Hughes, Jim R.;

In the era of genome-wide association studies (GWAS) and personalized medicine, predicting the impact of single nucleotide polymorphisms (SNPs) in regulatory elements is an important goal. Current approaches to determine the potential of regulatory SNPs depend on inadeq... View more
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