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Mikrobioomil põhinevad ennustusmudelid soolevähi diagnoosimiseks

Authors: Bulõgina, Triin;

Mikrobioomil põhinevad ennustusmudelid soolevähi diagnoosimiseks

Abstract

Inimesega seotud mikroorganismide ehk mikrobioomi uurimisvaldkond on muutunud väga oluliseks personaalmeditsiini arengus. Sellest lähtuvalt uuritakse bakalaureusetöös mikrobioomi kasutamist soolevähi diagnoosimiseks. Bakalaureusetöö eesmärk on luua soolevähi ennustusmudelid, kasutades lisaks klassikalistele soolevähi riskiteguritele soolestiku mikrobioomi andmeid. Mudelite koostamisel tutvustatakse Selbal metoodikat, mis on väljatöötatud mikrobioomi andmete analüüsimiseks. Meetodit kasutades luuakse soolevähi ennustusmudelid viie erineva populatsiooni andmetel ning hinnatakse prognoosimudelite ennustusvõimet soolevähi diagnoosimiseks ning mudelite üldistusvõimet teistesse populatsioonidesse.

Country
Estonia
Related Organizations
Keywords

mikrobioom, ROC-kõver, microbiome, prediction models, colorectal cancer, ennustusmudelid, ROC-curve, soolevähk

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  • citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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