Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus

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Zeng, Chenjie ; Guo, Xingyi ; Long, Jirong ; Kuchenbaecker, Karoline B. ; Droit, Arnaud ; Michailidou, Kyriaki ; Ghoussaini, Maya ; Kar, Siddhartha ; Freeman, Adam ; Hopper, John L. ; Milne, Roger L. ; Bolla, Manjeet K. ; Wang, Qin ; Dennis, Joe ; Agata, Simona ; Ahmed, Shahana ; Aittomaki, Kristiina ; Andrulis, Irene L. ; Anton-Culver, Hoda ; Antonenkova, Natalia N. ; Arason, Adalgeir ; Arndt, Volker ; Arun, Banu K. ; Arver, Brita ; Bacot, Francois ; Barrowdale, Daniel ; Baynes, Caroline ; Beeghly-Fadiel, Alicia ; Benitez, Javier ; Bermisheva, Marina ... view all 50 authors (2016)

Background: Multiple recent genome-wide association studies (GWAS) have identified a single nucleotide polymorphism (SNP), rs10771399, at 12p11 that is associated with breast cancer risk. Method: We performed a fine-scale mapping study of a 700 kb region including 441 g... View more