Morphogenetic movements during cranial neural tube closure in the chick embryo and the effect of homocysteine.

Brouns, M.R.; Afman, L.A.; Vanhauten, B.A.; Hekking, J.W.M.; Köhler, E.S.; van Straaten, H.W.;
  • Subject: spinal neurulation | Central Nervous System/embryology | mouse embryos | cell-shape | convergent extension | Actins/metabolism | Neural Tube Defects/physiopathology | rat embryos | plate | initial closure | risk factor | Actin Cytoskeleton/metabolism | Methylation | defects | Cell Movement/physiology | Homocysteine/physiology | Animals | Skull/embryology | Chick Embryo | mechanisms

In order to unravel morphogenetic mechanisms involved in neural tube closure, critical cell movements that are fundamental to remodelling of the cranial neural tube in the chick embryo were studied in vitro by quantitative time-lapse video microscopy. Two main direction... View more
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