DNA synthesis in ataxia telangiectasia

Doctoral thesis English OPEN
Jaspers, Nicolaas;
  • Publisher: Erasmus University Rotterdam

textabstractAfter the discovery that cultured cells from AT patients are hypersensitive to ionizing radiation the suggestion was made that AT-could be the 1 X-ray-analogue 1 of xeroderma pigmentosum. The latter syndrome (XP) is characterized by hypersensitivity to short... View more
  • References (14)
    14 references, page 1 of 2

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    Houldsworth, J.. and M.F. Lavin (1980) Effect of ionizing radiation on DNA :-.ynthe:-.i:-. in ;;to.xia tclangicct~ia cells, Nucleic Acids Res.. 8. 3709-3720.

    J01>pcrs. N.G.J.. J. de Wit and D. Bootsma (1982) in: B.A. Bridge). and D.G. Harnden (Eds.). Ataxia telangiectasia: a Cellular and Molecular Link Between Can<.:er. Neuropathology and Immune Deficiency. Wiley. Chichester. in pre:-.s.

    Kraemer. K.H. ( 1977) Progrc:-.sive degenerative di.\C.:t.\Cs a:-.:-.rn:i:.ttcd with dcfc<.:tivc DNA repair: xerodcrm;; pigmentosum and ;.ltaxia tclangiecta.\i:.t. in: W.W. l"ichoh and D. Murphy (Ed:-..). DNA Repair Processes and Cellular Sene:.cence. Sympo:-.ia Speciali~b. Miami. FL. pp. 37-71.

    Lehmann. A.R., and M.R. James (19:.:2) in: B.A. Bridge~ :.tnd D. G. Harnden (Ed:-..). Ataxia tclang.iecta:-.i~~= a Cellular and Molecular Link Between Can(:er. 1\.'curopo.thology and Immune Dcficient:y. Wiley. Chichester. in press.

    Painter, R.B.. and B.R. Young ( \980) Radiosensitivity in ataxia tclangicct:bia: a new explanation. Proc. Natl. Acad. Sci. (U.S.A), 77,7315-7317.

    Paterson. M.C.. B. Smith. P.H.M. Lohmann. AK. Anderson and L Fishman (1976) Defective excision repair of gamma-ray damaged DNA in human (ataxia telangiectasia) fibrobl~ts, Nature (London), 260,444-447.

    Patcr.:;on. M.C., B. Smith, P. Knight and A.K. Anderson ( 1977) Ataxi::l. telangiectasia: an inherited humJ.n disc~c involving radiosensitivity. malignancy and defective DNA repair, in: A. Castcllo.ni (Ed.}. Research in Photobiology. Plenum, New York, pp. 207-218.

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