Congenital cytomegalovirus infection: disease burden and screening tools : towards newborn screening
Vries, Jutte Jacoba Catharina de
mesheuropmc: otorhinolaryngologic diseases | virus diseases
Cytomegalovirus (CMV) infection is the most common congenital viral infection worldwide. The symptom of congenital CMV infection encountered most frequently is sensorineural hearing loss, which will affect approximately one out of ﬁve congenitally infected newborns. Because of the late-onset nature of the hearing loss, up to half of the children with congenital CMV-related hearing loss may not be detected in the newborn hearing screening. This thesis addresses several aspects of congenital CMV infection in general and more specifically in the Netherlands, in order to determine the necessity and feasibility of newborn screening for congenital CMV.