Scaling-up vaccine production: implementation aspects of a biomass growth observer and controller

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Soons, Zita I. T. A.; van den IJssel, Jan; van der Pol, Leo A.; van Straten, Gerrit; van Boxtel, Anton J. B.;
(2009)

Abstract This study considers two aspects of the implementation of a biomass growth observer and specific growth rate controller in scale-up from small- to pilot-scale bioreactors towards a feasible bulk production process for whole-cell vaccine against whooping cough. ... View more
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