publication . Article . 2008

Mortality and preoperative cardiac function in vascular amputees: an N-terminal pro-brain natriuretic peptide (NT-proBNP) pilot study

Dirk Jan van Veldhuisen; Frits A.J. Muskiet; Marcel Riemersma; Jan H. B. Geertzen; Pieter U. Dijkstra; Jan A.M.M. van den Dungen;
Open Access English
  • Published: 01 Jan 2008
Objective: To determine preoperative ventricular function in vascular amputees by measuring N-terminal pro-brain natriuretic peptide (NT-proBNP) and to analyse the relationship between NT-proBNP levels and 30-day postoperative mortality. Design: Prospective pilot study.Subjects and methods: In 19 patients planned for a lower limb amputation for non-reconstructable peripheral arterial disease NT-proBNP was measured the day before amputation.Results: Four amputees died within 30 days after the amputation. In 17 of 19 patients NT-proBNP values were found more than 2 standard deviations above the age corrected reference value. Pre-amputation NT-proBNP levels did not...
Medical Subject Headings: cardiovascular diseaseshormones, hormone substitutes, and hormone antagonists
free text keywords: Physical Therapy, Sports Therapy and Rehabilitation, Rehabilitation, N-terminal pro-Brain Natriuretic Peptide, Natriuretic peptide, medicine.drug_class, medicine, Amputation, medicine.medical_treatment, Lower limb amputation, Ventricular function, Cardiology, medicine.medical_specialty, business.industry, business, Peripheral, Surgery, Postoperative mortality, Cardiac function curve, Internal medicine
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