publication . Article . 1997

Dead space and slope indices from the expiratory carbon dioxide tension-volume curve

Kars, Alice; Bogaard, Jan; Stijnen, Theo; Vries, J.; Verbraak, Anton; Hilvering, C.;
Open Access English
  • Published: 01 Aug 1997
  • Country: Netherlands
textabstractThe slope of phase 3 and three noninvasively determined dead space estimates derived from the expiratory carbon dioxide tension (PCO2) versus volume curve, including the Bohr dead space (VD,Bohr), the Fowler dead space (VD,Fowler) and pre-interface expirate (PIE), were investigated in 28 healthy control subjects, 12 asthma and 29 emphysema patients (20 severely obstructed and nine moderately obstructed) with the aim to establish diagnostic value. Because breath volume and frequency are closely related to CO2 elimination, the recording procedures included varying breath volumes in all subjects during self-chosen/natural breathing frequency, and fixed ...
Medical Subject Headings: respiratory tract diseasesrespiratory system
free text keywords: *Carbon Dioxide, *Respiration, *Respiratory Dead Space, Adult, Airway Obstruction/diagnosis/physiopathology, Asthma/diagnosis/physiopathology, Discriminant Analysis, Emphysema/diagnosis/physiopathology, Female, Humans, Male, Middle aged, Reference Values, Tidal Volume
Related Organizations
Download from
29 references, page 1 of 2

Worth H. Expiratory partial pressure curves in the diagnosis of emphysema. Bull Eur Physiopathol Respir 1986; 22: 191-199.

Kars AH, Goorden G, Stijnen T, Bogaard JM, Verbraak AFM, Hilvering C. Does phase 2 of the expiratory PCO2 versus volume curve have diagnostic value in emphysema patients? Eur Respir J 1995; 8: 86-92. [OpenAIRE]

Clin Sci 1957; 16: 549-565.

Thesis. Berlings, Arlöv, Sweden, 1980.

Fletcher R, Jonson B, Cumming G, Brew J. The concept of deadspace with special reference to the single breath test for carbon dioxide. Br J Anaesth 1984; 56: 77-87.

Fowler WS. Lung functions studies. II. The respiratory dead space. Am J Physiol 1948; 154: 405-416. [OpenAIRE]

Bartels J, Severinghaus JW, Forster RE, Briscoe WA, Bates DV. The respiratory dead space measured by single breath analysis of oxygen, carbon dioxide, nitrogen or helium. J Clin Invest 1954; 33: 41-48. [OpenAIRE]

Wolff G, Brunner JX. Series dead space volume assessed as the mean value of a distribution function. Int J Clin Mon Comp 1984; 1: 177-181.

American Thoracic Society. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. Am Rev Respir Dis 1987; 136: 225-243.

Pratt PC. Role of conventional chest radiography in diagnosis and exclusion of emphysema. Am J Med 1987; 82: 998-1006.

Bull Eur Physiopath Resp 1983; 19, Suppl. 5: 1-95.

Yernault JC, Paiva M. The in vivo diagnosis of emphysema: an uncompletely resolved issue. Bull Eur Physiopathol Resp 1986; 22: 95-97.

Engel LA. Intraregional gas mixing and distribution. In: Engel LA, Paiva M, eds. Gas mixing and Distribution in the Lung. Lung Biology in Health and Disease, vol. 25; New York, Marcel Dekker, Inc. 1985: pp.

Meyer M, Mohr M, Schulz H, Piiper J. Sloping alveolar plateaus of CO2, O2, and intravenously infused C2H2 and CHClF2 in the dog. Resp Physiol 1990; 81: 137-152.

Dolffuss RE, Milic-Emili J, Bates DV. Regional ventilation of the lung, studied with boluses of Xenon133.

29 references, page 1 of 2
Powered by OpenAIRE Open Research Graph
Any information missing or wrong?Report an Issue