publication . Article . 2016

Emergence of flagellar beating from the collective behavior of individual ATP-powered dyneins

S. Namdeo; P. R. Onck;
Open Access English
  • Published: 10 Oct 2016
Abstract
Flagella are hair-like projections from the surface of eukaryotic cells, and they play an important role in many cellular functions, such as cell-motility. The beating of flagella is enabled by their internal architecture, the axoneme, and is powered by a dense distribution of motor proteins, dyneins. The dyneins deliver the required mechanical work through the hydrolysis of ATP. Although the dynein-ATP cycle, the axoneme microstructure, and the flagellar-beating kinematics are well studied, their integration into a coherent picture of ATP-powered flagellar beating is still lacking. Here we show that a time-delayed negative-work-based switching mechanism is able...
Subjects
free text keywords: HEADED PROCESSIVE MOTOR, SLIDING FILAMENT MODEL, SPERM FLAGELLA, SEA-URCHIN, FLEXURAL RIGIDITY, AXONEMAL DYNEIN, BEND PROPAGATION, MOLECULAR MOTORS, MECHANICAL-PROPERTIES, THERMAL FLUCTUATIONS, To be checked by Faculty, Dynein, Collective behavior, Axoneme, Molecular motor, Nanotechnology, Biophysics, Microtubule, Flagellum, Physics, Classical mechanics, Motor protein, Nexin, biology.protein, biology
Related Organizations
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