Aggregation and toxicity of amyloid-beta peptide in relation to peptide sequence variation

Doctoral thesis English OPEN
Vandersteen, A.;
(2012)
  • Publisher: Universiteit Twente
  • Subject: METIS-288677 | IR-81970

Generally, aggregation of the amyloid-ß peptide is considered the cause of neuronal death in Alzheimer disease. The heterogenous Aß peptide occurs in various lengths in vivo: Aß40 and Aß42 are the predominant forms while both shorter and longer peptides exist. Aß40 and ... View more
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