publication . Article . 2010

Cold-induced vasoconstriction at forearm and hand skin sites: the effect of age

Brm Boris Kingma; Ajh Arjan Frijns; Whm Wim Saris; van Aa Anton Steenhoven; van Wd Wouter Marken Lichtenbelt;
Open Access English
  • Published: 01 Mar 2010 Journal: European Journal of Applied Physiology, volume 109, issue 5, pages 915-921 (issn: 1439-6319, eissn: 1439-6327, Copyright policy)
  • Publisher: Springer-Verlag
  • Country: Netherlands
Abstract
During mild cold exposure, elderly are at risk of hypothermia. In humans, glabrous skin at the hands is well adapted as a heat exchanger. Evidence exists that elderly show equal vasoconstriction due to local cooling at the ventral forearm, yet no age effects on vasoconstriction at hand skin have been studied. Here, we tested the hypotheses that at hand sites (a) elderly show equal vasoconstriction due to local cooling and (b) elderly show reduced response to noradrenergic stimuli. Skin perfusion and mean arterial pressure were measured in 16 young adults (Y: 18-28 years) and 16 elderly (E: 68-78 years). To study the effect of local vasoconstriction mechanisms lo...
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Subjects
free text keywords: Original Article, Thermoregulation, Aging, Glabrous skin, Public Health, Environmental and Occupational Health, Physiology (medical), Orthopedics and Sports Medicine, General Medicine, Comparative Study, Journal Article, Research Support, Non-U.S. Gov't, Research Support, Non-U.S. Gov't, Mean arterial pressure, Bretylium, medicine.drug, medicine, Cardiology, medicine.medical_specialty, business.industry, business, Ageing, Anesthesia, Forearm, medicine.anatomical_structure, Hypothermia, medicine.symptom, Internal medicine, Sympathetic nervous system, Vasoconstriction
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