No Evidence for Systemic Platelet Activation During or After Orthotopic Liver Transplantation

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Pereboom, Ilona T A; Adelmeijer, Jelle; van Leeuwen, Yvonne; Hendriks, Herman G D; Porte, Robert J; Lisman, Ton;
(2009)
  • Subject: TISSUE PLASMINOGEN-ACTIVATOR | BETA-THROMBOGLOBULIN | THROMBIN GENERATION | P-SELECTIN | CIRRHOSIS | DISEASE | COAGULATION | HEMOSTASIS | EXPRESSION | PATHOPHYSIOLOGY | UMCG Approved

Platelet function is thought to deteriorate during liver transplantation as a result of platelet activation and proteolysis of platelet receptors by plasmin following reperfusion. However, this hypothesis has never been formally tested. Twenty patients undergoing a firs... View more
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