publication . Article . 2009

Effects of exercise training in patients with idiopathic pulmonary arterial hypertension

de Man, F.S.; Handoko, M.L.; Groepenhoff, H.; van 't Hul, A.J.; Abbink, J.; Koppers, R.J.H.; Grotjohan, H.P.; Twisk, J.W.R.; Bogaard, H.J.; Boonstra, A.; ...
Open Access
  • Published: 31 Aug 2009 Journal: Yearbook of Sports Medicine, volume 2,010, pages 249-251 (issn: 0162-0908, Copyright policy)
  • Publisher: Elsevier BV
  • Country: Netherlands
Abstract
We determined the physiological effects of exercise training on exercise capacity and quadriceps muscle function in patients with idiopathic pulmonary arterial hypertension (iPAH). In total, 19 clinically stable iPAH patients (New York Heart Association II-III) underwent a supervised exercise training programme for the duration of 12 weeks. Maximal capacity, endurance capacity and quadriceps function were assessed at baseline and after 12 weeks. In 12 patients, serial quadriceps muscle biopsies were obtained. 6-min walk distance and peak exercise capacity did not change after training. However, endurance capacity improved significantly after training, demonstrat...
Subjects
Medical Subject Headings: education
free text keywords: Medicine, business.industry, business, Idiopathic Pulmonary Arterial Hypertension, Physical therapy, medicine.medical_specialty, Pulmonary and Respiratory Medicine, Artery, medicine.anatomical_structure, Anaerobic exercise, Respiratory disease, medicine.disease, Diabetes mellitus, Physical exercise, Pulmonary hypertension, Aerobic capacity
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