publication . Doctoral thesis . 2008

Evaluation of new drugs in daily clinical practice: anti-TNF alpha in rheumatoid arthritis patients.

Kievit, W.;
Open Access
  • Published: 01 Jan 2008
  • Publisher: [S.l. : s.n.]
  • Country: Netherlands
The objective of this thesis was to explore the value and the validity of data collected in daily clinical practice for drug evaluation and cost-effectiveness studies, using data collected on TNFa blocking agents in rheumatoid arthritis. First, the need for and value of information from daily clinical practice was researched. Together, the results of Chapters 3, 4 and 5 illustrated that treatment of RA patients with anti-TNFa blocking agents in daily clinical practice was different from what was expected from the performed RCTs and the guidelines developed on the basis of the RCTs. Data from a daily clinical practice registry can be used to get insight in the ac...
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Doctoral thesis . 2008
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