publication . Article . Other literature type . 1994

Androgen receptor expression in human ovarian and uterine tissue of long term androgen-treated transsexual women

Savi Chadha; Thierry D. Pache; Frans J.M. Huikeshoven; Albert O. Brinkmann; Theodorus H. van derKwast;
Open Access English
  • Published: 01 Nov 1994 Journal: Human Pathology, volume 25, issue 11, pages 1,198-1,204 (issn: 00468177, Copyright policy)
  • Country: Netherlands
textabstractAndrogen receptor (AR) modulation in human uteri and ovaries of long term androgen-treated transsexual female patients was investigated. Androgen receptor expression was evaluated immunohistochemically in the ovaries of 11 and the endometria and myometria of six androgen-treated transsexual female patients. This was compared with AR expression in the ovaries and uteri of premenopausal and postmenopausal women not receiving treatment and in 10 ovaries of female patients with polycystic ovarian disease (PCOD). In the normal ovaries germinal epithelium, granulosa cells of antral follicles, corpus luteum, and thecal and stromal cells exhibited moderate A...
Persistent Identifiers
free text keywords: Polycystic ovarian disease, Immunohistochemistry, Antral follicle, Internal medicine, medicine.medical_specialty, medicine, Immunostaining, Biology, Androgen, medicine.drug_class, Germinal epithelium, Endocrinology, Corpus luteum, medicine.anatomical_structure, Androgen receptor
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