publication . Article . Other literature type . 1994

Androgen receptor expression in human ovarian and uterine tissue of long term androgen-treated transsexual women

Chadha, Savi; Pache, Thierry D.; Huikeshoven, Frans J.M.; Brinkmann, Albert O.; van derKwast, Theodorus H.;
Open Access
  • Published: 01 Nov 1994 Journal: Human Pathology, volume 25, pages 1,198-1,204 (issn: 0046-8177, Copyright policy)
  • Publisher: Elsevier BV
  • Country: Netherlands
Abstract
textabstractAndrogen receptor (AR) modulation in human uteri and ovaries of long term androgen-treated transsexual female patients was investigated. Androgen receptor expression was evaluated immunohistochemically in the ovaries of 11 and the endometria and myometria of six androgen-treated transsexual female patients. This was compared with AR expression in the ovaries and uteri of premenopausal and postmenopausal women not receiving treatment and in 10 ovaries of female patients with polycystic ovarian disease (PCOD). In the normal ovaries germinal epithelium, granulosa cells of antral follicles, corpus luteum, and thecal and stromal cells exhibited moderate A...
Subjects
free text keywords: Anatomy, Germinal epithelium, Biology, Immunohistochemistry, Corpus luteum, medicine.anatomical_structure, medicine, Internal medicine, medicine.medical_specialty, Antral follicle, Endocrinology, Polycystic ovarian disease, Androgen receptor, Immunostaining, Androgen, medicine.drug_class
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publication . Article . Other literature type . 1994

Androgen receptor expression in human ovarian and uterine tissue of long term androgen-treated transsexual women

Chadha, Savi; Pache, Thierry D.; Huikeshoven, Frans J.M.; Brinkmann, Albert O.; van derKwast, Theodorus H.;