LIVER METASTASIS MODEL OF COLON-CANCER IN THE RAT - IMMUNOHISTOCHEMICAL CHARACTERIZATION

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THOMAS, C; NIJENHUIS, AM; TIMENS, W; KUPPEN, PJK; DAEMEN, T; SCHERPHOF, GL;
(1993)
  • Subject: EXPERIMENTAL LIVER METASTASIS | CC531 COLON ADENOCARCINOMA | IMMUNOHISTOCHEMISTRY | WAG/RIJ RATS | KUPFFER CELLS | MONOCYTES | LYMPHOCYTES | PIT CELLS | POLYMORPHONUCLEAR LEUKOCYTES | NATURAL-KILLER CELLS | MONOCLONAL-ANTIBODY | TUMOR SITE | MACROPHAGES | SUBPOPULATIONS | RESECTION | CARCINOMA | CYTOKINES | INVITRO

Inoculation of 3 x 10(4) to 3 x 10(5) CC531 colon adenocarcinoma cells into the portal vein of syngeneic WAG/Rij rats provides a reproducible animal model of colon cancer liver metastasis with macroscopically visible tumor nodules at day 25 after inoculation. In this st... View more
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