Protein-protein interaction between caveolin-1 and SHP-2 is dependent onthe N-SH2 domain of SHP-2

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Park, Hyunju; Ahn, Keun Jae; Kang, Jihee Lee; Choi, Youn-Hee;

Src homology 2-containing protein tyrosine phosphatase 2 (SHP-2) is known to protect neurons from neurodegeneration during ischemia/reperfusion injury. We recently reported that ROS-mediated oxidative stress promotes phosphorylation of endogenous SHP-2 in astrocytes and... View more
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