Total Synthesis of Natural Products of Microbial Origins(Recent Topics of the Agricultunal Biological Science in Tohoku University)

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Hiromasa, KIYOTA ; Shigefumi, KUWAHARA ; Laboratory of Applied Bioorganic Chemistry, Division of Bioscience & Biotechnology for Future Bioindustries, Graduate School of Agricultural Science, Tohoku University ; Laboratory of Applied Bioorganic Chemistry, Division of Bioscience & Biotechnology for Future Bioindustries, Graduate School of Agricultural Science, Tohoku University (2008)
  • Journal: Tohoku journal of agricultural research, volume 58, issue 3/4, pages 167-173 (issn: 0040-8719)

Microorganisms are an important rich source of secondary metabolites, which could be useful leads to valuable agrochemicals and/or medicinal drugs. This mini-review describes our recent achievements on the total synthesis of biologically active natural products of microbial origins: pteridic acids A and B (strong plant growth promoters), epoxyquinols A and B (anti-angiogenic compounds), communiols A-F, G, and H, and macrotetrolide α (antibiotics), pyricuol and tabtoxinine-β-lactam (phytotoxins).
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