Inhibitory effect of apicidin on in vitro and in vivo growth of Babesia parasites

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Munkhjargal, T; Aboulaila, M.R.A; Sivakumar, T; Yokoyama, Naoaki; Igarashi, Ikuo;
(2009)
  • Publisher: National Research Center for Protozoan Diseases
  • Journal: The journal of protozoology research,volume 19,issue 1,pages42-49 (issn: 0917-4427)
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  • Subject: Apicidin | B .bovis | B .bigemina | B. microti | asexual growth

Apicidin, a histone deacetylase inhibitor, has a broad spectrum of anti-protozoal activities against apicomplexan parasites. In the present study, we evaluated the inhibitory effect of apicidin on the asexual growth of bovine Babesia parasites (B. bovis and B. bigemina)... View more
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