Osteoblast Differentiation and Bone Formation Gene Expression in Strontium-inducing Bone Marrow Mesenchymal Stem Cell

Research English OPEN
SILA-ASNA, MONNIPHA; BUNYARATVEJ, AHNOND; Maeda, Sakan; Kitaguchi, Hiromichi; BUNYARATAVEJ, NARONG;
(2007)
  • Publisher: 神戸大学医学部
  • Journal: The Kobe journal of the medical sciences,volume 53,issue 1,pages25-35 (issn: 0023-2513)
  • Subject: mesenchymal stem cell | Cbfa1 (Runx2) | strontium | osteocalcin | bone formation | osteoblasts
    mesheuropmc: inorganic chemicals | musculoskeletal diseases

Osteoblastic differentiation from human mesenchymal stem cell (hMSCs) is animportant step of bone formation. We studied the in vitro induction of hMSCs byusing strontium ranelate, a natural trace amount in water, food and human skeleton.The mRNA synthesis of various ost... View more
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