Mechanism of induction of posterior vitreous detachment by intravireal plasmin infection, and development of a novel enzyme for pharmacologic vitreolysis

Doctoral thesis English OPEN
髙野, 晃臣; タカノ, アキオミ; Takano, Akiomi;
  • Publisher: 熊本大学

We demonstrated a dose-dependent increase in levels of active matrix metalloproteinase (MMP)-2 in the vitreous after plasmin injection. The time course of MMP-2 activity after plasmin administration showed that MMP-2 was significantly activated at 5 and 15 min after inj... View more
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